Optimizing Adaptive Design for Phase 2 Dose-finding Trials Incorporating Long-term Success and Financial Considerations: A Case Study for Neuropathic Pain

Exact Inference for Adaptive Group Sequential Designs

Optimizing Trial Design; Sequential, Adaptive and Enrichment Strategies

A Network Algorithm for Performing Fisher’s Exact Test in r × c Contingency Tables

Exact Permutational Tests for Group Sequential Clinical Trials

Exact Logistic Regression: Theory and Examples

Efficient Monte Carlo Methods for Conditional Logistic Regression

Adaptive Increase in Sample Size When Interim Results are Promising: A Practical Guide with Examples

Authors’ Response to “Comment on Adaptive Increase in Sample Size When Interim Results are Promising”

Early Clinical Development Planning via Biomarkers, Clinical Endpoints, and Simulation: A Case Study to Optimize for Phase 3 Dose Selection