Author: Mehta, C.R.Schäfer, H.Daniel, H.Irle, S.Statistics in Medicine, 33(26), pp. 4515–4531. Mehta, C.R., Schäfer, H., Daniel, H. and Irle, S. http://onlinelibrary.wiley.com/doi/10.1002/sim.6272/abstract Interest: Adaptive Methods